Hello everyone, I am feeling really frustrated and down today. I have been having nonstop outbreaks since being diagnosed with HSV-2 back in October, 2009. My doctor initially misdiagnosed it and then put me on Valtrex 500mg twice daily. I continued at 500mg daily for suppression, but thats not working. I have prodromal symptoms every 3-4 days (burning, shooting pains down L. inner thigh, itching) and then develop redness and itching externally on vagina and around anus. I also sometimes get pimple like sores in anal area and have burning with urination and a feeling almost like menstrual cramps. Also a lot of vaginal discharge and odor at times too. I have not had sex with my boyfriend since getting diagnosed because I am never without symptoms. This really sucks!! I have been treated for BV twice without much relief, and I'm at my wits end. I went back to see my doc and she basically told me I wasn't really having outbreaks zsince there were no blisters present, and that I should just stop the valtrex since it isn't really working. That was sure helpful!! I have completely cut out nuts and seeds from my diet. I have also tried Lysine, Echinacea, Vit B, C, and zinc off and on and am considering trying a higher dose of Valtrex. This has to end!! For those who are using Valtrex 1000mg suppressively, how long does it take to start working? Also, if you are taking all the supplements consistently, how long does that take to start working. I have plans to go on some vacations this summer with my boyfriend and would love to be able to have sex with him again. Any help or advice would be greatly appreciated. Thanks!!